The 5 Best vitamins for energy and tiredness

In today’s relentless world, most of us wake up already tired—chugging coffee just to function, battling brain fog, and dragging through the day despite “enough” sleep. This isn’t normal fatigue; it’s stress fatigue, and it’s draining your life. The good news? Our guide to the best vitamins for energy and tiredness can deliver steady, non-jittery energy and true recovery without relying on stimulants.

We didn’t chase trends. We analyzed over 40 top-selling fatigue supplements, prioritizing only those backed by clinical studies for stress resilience, cellular energy, and deeper sleep. Each finalist earned its spot through verified ingredient quality, third-party testing, and real-world performance. Here are the six that rose to the top.

Best Vitamins at a glance

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1. Bronson Vitamin B-Complex with C

This all-in-one capsule delivers a full spectrum of $\text{B}$-vitamins plus Vitamin , making it one of the best vitamins for energy and tiredness when used daily for foundational support without the crash.

• Quality : Packs all 8 essential B vitamins (B1, B2, B3, B5, B6, B7, B9, B12) plus Vitamin C in a single, easy-to-take dose.
• Safety – Non-GMO, Gluten-Free, Soy-Free, and made in a GMP-Certified facility trusted since 1960.
• Performance – Fuels natural energy metabolism, supports nervous system calm, and boosts immune defense—no stimulants, just reliable daily support.
• Overall Score: 9.0/10 The best budget-friendly foundational B-complex for anyone wanting consistent energy and wellness without breaking the bank.

2. KSM-66 Ashwagandha

This potent adaptogen supplement features a full-spectrum root extract that helps your body manage stress and restore natural energy balance, making it an essential complement to your regimen of vitamins for energy and tiredness without the jitters.

• Quality – Delivers 600mg of clinically studied KSM-66 per serving, a high-potency, organic ashwagandha extract standardized to 5% withanolides for reliable results.
• Safety – Non-GMO, vegan, gluten-free, and rigorously third-party tested in GMP-certified facilities for purity and potency.
• Performance – Lowers cortisol levels to combat stress fatigue, enhances endurance, and supports better sleep for sustained daily vitality and mental clarity.
• Overall Score: 9.4/10 A top-tier adaptogen choice for high-stress pros seeking calm energy and resilience on a budget.

3. Super Ubiquinol CoQ10

This advanced CoQ10 formula uses the highly bioavailable ubiquinol form to support heart health and cellular energy production for fatigue-fighting vitality.

• Quality – Provides 200mg of ubiquinol, the active form of CoQ10, enhanced with PrimaVie shilajit for superior absorption and potency.
• Safety – Non-GMO, gluten-free, and manufactured in GMP-certified facilities with rigorous third-party testing for purity.
• Performance – Boosts mitochondrial energy at the cellular level, reduces oxidative stress, and promotes endurance to combat daily fatigue and support overall resilience.
• Overall Score: 9.6/10

An elite, absorbable CoQ10 option for professionals needing sustained cellular energy without stimulants.

4. Solgar Gentle Iron

This gentle iron supplement provides 25mg of iron bisglycinate per capsule, designed to combat fatigue from low iron levels without the typical stomach upset.

• Quality – Features chelated iron bisglycinate for superior absorption and bioavailability, backed by Solgar’s 75+ years of supplement expertise.
• Safety – Non-GMO, vegan, gluten-free, and free from common allergens, with third-party testing in GMP-certified facilities.
• Performance – Supports red blood cell production and oxygen transport to fight tiredness, while being easy on the digestive system for daily use.
• Overall Score: 9.5/10

A reliable, stomach-friendly iron option for those battling fatigue from deficiency, offering effective replenishment without discomfort.

5. Pure Encapsulations Magnesium

This high-quality magnesium glycinate supplement offers 120mg per capsule to support muscle relaxation, stress relief, and steady energy levels without digestive upset.

• Quality – Provides bioavailable magnesium glycinate, a gentle form that’s easily absorbed, from a brand renowned for hypoallergenic, research-backed formulations.
• Safety – Hypoallergenic, non-GMO, gluten-free, vegan, and third-party tested in GMP-certified facilities for ultimate purity.
• Performance – Promotes calm nervous system function, reduces muscle tension from fatigue, and aids restorative sleep for better daily recovery.
• Overall Score: 9.8/10

An exceptional choice for stress-induced fatigue, delivering gentle, effective magnesium support for sustained calm and vitality.

Your Path to Lasting Energy

From the foundational boost of Bronson Vitamin B-Complex with C to the stress-taming power of KSM-66 Ashwagandha, cellular support of Super Ubiquinol CoQ10, gentle replenishment with Solgar Gentle Iron, and deep recovery enabled by Pure Encapsulations Magnesium, these six supplements stand out as science-backed solutions to fatigue. Each targets a key driver—stress, nutrient gaps, oxygen delivery, or sleep quality—giving you a complete toolkit for steady, non-jittery energy.

Ready to reclaim your vitality? Start with one or two that match your needs, stay consistent, and listen to your body. And if you’re hungry for more ways to feel your best, check out our guides on

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